U.S. stocks mixed at close of trade; Dow Jones Industrial Average up 0.12%

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At the close in NYSE, the Dow Jones Industrial Average rose 0.12%, while the S&P 500 index gained 0.07%, and the NASDAQ Composite index lost 0.11%.

The best performers of the session on the Dow Jones Industrial Average were Merck & Company Inc (NYSE:MRK), which rose 3.95% or 4.22 points to trade at 111.10 at the close. Meanwhile, Apple Inc (NASDAQ:AAPL) added 1.85% or 2.80 points to end at 153.83 and Coca-Cola Co (NYSE:KO) was up 1.55% or 0.92 points to 60.36 in late trade.

The worst performers of the session were Dow Inc (NYSE:DOW), which fell 2.07% or 1.21 points to trade at 57.11 at the close. Walgreens Boots Alliance Inc (NASDAQ:WBA) declined 1.77% or 0.64 points to end at 35.45 and Intel Corporation (NASDAQ:INTC) was down 1.55% or 0.41 points to 25.99.

The top performers on the S&P 500 were Lumen Technologies Inc (NYSE:LUMN) which rose 4.10% to 3.30, Merck & Company Inc (NYSE:MRK) which was up 3.95% to settle at 111.10 and Enphase Energy Inc (NASDAQ:ENPH) which gained 3.77% to close at 225.35.

The worst performers were DexCom Inc (NASDAQ:DXCM) which was down 7.87% to 113.25 in late trade, Newell Brands Inc (NASDAQ:NWL) which lost 7.23% to settle at 13.48 and VF Corporation (NYSE:VFC) which was down 5.37% to 24.85 at the close.

The top performers on the NASDAQ Composite were Appreciate Holdings Inc (NASDAQ:SFR) which rose 152.89% to 3.06, Unicycive Therapeutics Inc (NASDAQ:UNCY) which was up 153.06% to settle at 1.24 and Bellerophon Therapeutics Inc (NASDAQ:BLPH) which gained 94.11% to close at 3.51.

The worst performers were Aclaris Therapeutics Inc (NASDAQ:ACRS) which was down 44.68% to 7.07 in late trade, Rubius Therapeutics Inc (NASDAQ:RUBY) which lost 33.55% to settle at 0.08 and Embark Technology Inc (NASDAQ:EMBK) which was down 32.81% to 2.56 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 1972 to 1052 and 97 ended unchanged; on the Nasdaq Stock Exchange, 2429 fell and 1234 advanced, while 125 ended unchanged.

Shares in Aclaris Therapeutics Inc (NASDAQ:ACRS) fell to 52-week lows; down 44.68% or 5.71 to 7.07. Shares in Rubius Therapeutics Inc (NASDAQ:RUBY) fell to 3-years lows; falling 33.55% or 0.04 to 0.08. Shares in Bellerophon Therapeutics Inc (NASDAQ:BLPH) rose to 52-week highs; gaining 94.11% or 1.70 to 3.51.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was up 0.65% to 18.61.

Gold Futures for April delivery was down 0.12% or 2.20 to $1,852.40 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in April rose 1.10% or 0.88 to hit $80.56 a barrel, while the May Brent oil contract rose 0.55% or 0.47 to trade at $86.30 a barrel.

EUR/USD was unchanged 0.43% to 1.07, while USD/JPY rose 0.06% to 135.93.

The US Dollar Index Futures was down 0.20% at 104.28.