U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.49%

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At the close in NYSE, the Dow Jones Industrial Average fell 0.49%, while the S&P 500 index fell 1.42%, and the NASDAQ Composite index declined 2.51%.

The best performers of the session on the Dow Jones Industrial Average were Boeing Co (NYSE:BA), which rose 2.97% or 6.45 points to trade at 223.90 at the close. Meanwhile, Caterpillar Inc (NYSE:CAT) added 2.07% or 4.60 points to end at 227.00 and Walmart Inc (NYSE:WMT) was up 1.42% or 2.03 points to 145.47 in late trade.

The worst performers of the session were Microsoft Corporation (NASDAQ:MSFT), which fell 4.23% or 13.47 points to trade at 304.80 at the close. Salesforce.com Inc (NYSE:CRM) declined 3.87% or 9.20 points to end at 228.63 and Apple Inc (NASDAQ:AAPL) was down 1.90% or 3.34 points to 172.19.

The top performers on the S&P 500 were Biogen Inc (NASDAQ:BIIB) which rose 5.03% to 236.67, Kroger Company (NYSE:KR) which was up 4.96% to settle at 49.48 and American Airlines Group (NASDAQ:AAL) which gained 4.54% to close at 19.34.

The worst performers were ServiceNow Inc (NYSE:NOW) which was down 9.31% to 520.00 in late trade, Lumen Technologies Inc (NYSE:LUMN) which lost 7.67% to settle at 12.27 and Bio-Techne Corp (NASDAQ:TECH) which was down 7.16% to 397.68 at the close.

The top performers on the NASDAQ Composite were Singularity Future Technology Ltd (NASDAQ:SGLY) which rose 25.88% to 5.010, Medavail Holdings Inc (NASDAQ:MDVL) which was up 24.41% to settle at 1.58 and Vinco Ventures Inc (NASDAQ:BBIG) which gained 22.57% to close at 3.530.

The worst performers were Vyne Therapeutics Inc (NASDAQ:VYNE) which was down 21.45% to 0.785 in late trade, Kymera Therapeutics Inc (NASDAQ:KYMR) which lost 15.90% to settle at 42.68 and Kidpik Corp (NASDAQ:PIK) which was down 15.62% to 6.16 at the close.

Falling stocks outnumbered advancing ones on the New York Stock Exchange by 1785 to 1469 and 120 ended unchanged; on the Nasdaq Stock Exchange, 2648 fell and 1156 advanced, while 208 ended unchanged.

Shares in Kroger Company (NYSE:KR) rose to all time highs; rising 4.96% or 2.34 to 49.48. Shares in Vyne Therapeutics Inc (NASDAQ:VYNE) fell to all time lows; falling 21.45% or 0.214 to 0.785.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was up 15.27% to 20.31.

Gold Futures for February delivery was down 0.28% or 5.20 to $1822.10 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in February fell 1.17% or 0.97 to hit $81.67 a barrel, while the March Brent oil contract fell 0.08% or 0.07 to trade at $84.09 a barrel.

EUR/USD was up 0.03% to 1.1457, while USD/JPY rose 0.03% to 114.20.

The US Dollar Index Futures was down 0.05% at 94.850.