U.S. stocks lower at close of trade; Dow Jones Industrial Average down 0.12%

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At the close in NYSE, the Dow Jones Industrial Average fell 0.12%, while the S&P 500 index fell 0.16%, and the NASDAQ Composite index fell 0.45%.

The best performers of the session on the Dow Jones Industrial Average were Walgreens Boots Alliance Inc (NASDAQ:WBA), which rose 2.67% or 0.88 points to trade at 33.82 at the close. Meanwhile, Boeing Co (NYSE:BA) added 2.19% or 4.39 points to end at 204.96 and Dow Inc (NYSE:DOW) was up 1.75% or 0.91 points to 52.91 in late trade.

The worst performers of the session were American Express Company (NYSE:AXP), which fell 2.40% or 3.91 points to trade at 159.21 at the close. UnitedHealth Group Incorporated (NYSE:UNH) declined 1.93% or 9.32 points to end at 472.58 and Merck & Company Inc (NYSE:MRK) was down 1.31% or 1.40 points to 105.53.

The top performers on the S&P 500 were PVH Corp (NYSE:PVH) which rose 19.97% to 88.32, McCormick & Company Incorporated (NYSE:MKC) which was up 9.61% to settle at 81.18 and Carnival Corporation (NYSE:CCL) which gained 6.14% to close at 9.33.

The worst performers were Signature Bank (OTC:SBNY) which was down 99.81% to 0.13 in late trade, SVB Financial Group (OTC:SIVBQ) which lost 99.62% to settle at 0.40 and Humana Inc (NYSE:HUM) which was down 4.65% to 483.41 at the close.

The top performers on the NASDAQ Composite were Biomea Fusion Inc (NASDAQ:BMEA) which rose 99.03% to 30.71, Viking Therapeutics Inc (NASDAQ:VKTX) which was up 69.30% to settle at 15.44 and Greenbrook TMS Inc (NASDAQ:GBNH) which gained 50.17% to close at 1.13.

The worst performers were Signature Bank (OTC:SBNY) which was down 99.81% to 0.13 in late trade, SVB Financial Group (OTC:SIVBQ) which lost 99.62% to settle at 0.40 and Monopar Therapeutics Inc (NASDAQ:MNPR) which was down 51.18% to 1.45 at the close.

Rising stocks outnumbered declining ones on the New York Stock Exchange by 1782 to 1195 and 106 ended unchanged; on the Nasdaq Stock Exchange, 2053 fell and 1547 advanced, while 158 ended unchanged.

Shares in Signature Bank (OTC:SBNY) fell to all time lows; falling 99.81% or 69.87 to 0.13. Shares in SVB Financial Group (OTC:SIVBQ) fell to all time lows; falling 99.62% or 104.96 to 0.40. Shares in Biomea Fusion Inc (NASDAQ:BMEA) rose to all time highs; gaining 99.03% or 15.28 to 30.71. Shares in Signature Bank (OTC:SBNY) fell to all time lows; falling 99.81% or 69.87 to 0.13. Shares in Viking Therapeutics Inc (NASDAQ:VKTX) rose to 3-years highs; up 69.30% or 6.32 to 15.44. Shares in SVB Financial Group (OTC:SIVBQ) fell to all time lows; losing 99.62% or 104.96 to 0.40. Shares in Monopar Therapeutics Inc (NASDAQ:MNPR) fell to all time lows; losing 51.18% or 1.52 to 1.45.

The CBOE Volatility Index, which measures the implied volatility of S&P 500 options, was down 3.06% to 19.97.

Gold Futures for June delivery was up 0.97% or 19.15 to $1,990.65 a troy ounce. Elsewhere in commodities trading, Crude oil for delivery in May rose 0.80% or 0.58 to hit $73.39 a barrel, while the June Brent oil contract rose 0.64% or 0.50 to trade at $78.26 a barrel.

EUR/USD was unchanged 0.44% to 1.08, while USD/JPY fell 0.52% to 130.88.

The US Dollar Index Futures was down 0.42% at 102.09.