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Omnicom serves over 5,000 clients in 70 countries, including McDonald’s Corp (NYSE:MCD), Apple (NASDAQ:AAPL) and Johnson & Johnson (NYSE:JNJ).
The move emphasizes a growing skepticism among agencies and brands about the micro-blogging site’s future since Elon Musk took over the helm.
Omnicom did not immediately respond to a Reuters request for comment.
“The risk to our clients’ brand safety has risen sharply to a level most would find unacceptable,” the report added, citing the Omnicom memo.
Ad sales represented over 90% of Twitter’s revenue in the second quarter.
Last month, U.S. automaker General Motors Co (NYSE:GM) said it had temporarily halted paid advertising on Twitter.