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The pan-European STOXX 600 index slipped 0.5%, as of 0827 GMT. Gains in mining and oil & gas stocks were outweighed by losses in the travel & leisure sector following disappointing earnings from betting group Flutter.
Shell (LON:RDSa) inched up 0.4% after the London-listed energy major said it would exit all its Russian operations, including a major liquefied natural gas plant. Its stock fell 1.4% in the previous session.
Ceasefire talks between Russia and its southern neighbour held on Monday failed to reach a breakthrough and negotiators have not said when a new round would take place.
Shares of beaten-down stocks such as London-listed miner EVRAZ, which has a large exposure to Russia, rose 7.2% after suffering double-digit falls in the past few sessions.
German chemicals maker Covestro gained 3.7% after saying it had more than doubled its 2021 core profit and expected upbeat earnings for 2022.
Euro zone and UK factory activity readings are due later in the day.